I divided one 30 Arc-Second (~1km) Basic Demographic Characteristics raster by another and ended up with very high values in the result.
In order to control for this, we recommend that users consider lower spatial resolution versions of the data (2.5 Arc-Minute, 15 Arc-Minute, 30 Arc-Minute, or 1 Degree) in order to smooth away the artifact, or conversely impose a ceiling on map algebra operations at 30 Arc-Second resolution in order to snap extremely large artifacts to more realistic values.